Preimplantation
Genetic
Diagnosis
for BRCA 1/2 carriers

Psychological Considerations:

As a BRCA carrier, PGD may be seen as another difficult and emotionally-laden decision. Like other decisions associated with BRCA, PGD requires processing large amounts of highly technical information, and having to make decisions based on probabilistic information.

Different psychological considerations may influence how you feel about PGD. These may include your perception of the severity of carrying a BRCA mutation, and your feelings and attitudes about existing screening and prevention options. Other considerations may include your feelings about the benefits, risks, and costs associated with IVF and PGD, and your feelings about how you want to become a parent. IVF can be a physically and emotionally demanding procedure. If unsuccessful, you may have feelings of loss or disappointment.

As with other BRCA-related decisions, we recommend you evaluate your existing support resources, and seek additional support where needed. Different patients have different support needs, including emotional, informational, financial, and instrumental (e.g., help with getting to/from doctor’s appointments, time off work). Patients with prior or current psychological or psychiatric difficulties, including anxiety or depression, as well as those having difficulty with decision-making about PGD, may want to consult with a mental health professional (e.g., social worker, psychologist, psychiatrist) knowledgeable in this area for additional support.